After a ferry is bombed in New Orleans, an A.T.F. agent joins a unique investigation using experimental surveillance technology to find the bomber, but soon finds himself becoming obsessed with one of the victims.

A wave of kidnappings has swept through Mexico, feeding a growing sense of panic among its wealthier citizens, especially parents. In one six-day period, there were twenty-four abductions, leading many to hire bodyguards for their children. Into this world enters John Creasy, a burned-out ex-CIA operative/assassin, who has given up on life. Creasy's friend Rayburn brings him to Mexico City to be a bodyguard to nine-year-old Pita Ramos, daughter of industrialist Samuel Ramos and his wife Lisa. Creasy is not interested in being a bodyguard, especially to a youngster, but for lack of something better to do, he accepts the assignment. Creasy barely tolerates the precocious child and her pestering questions about him and his life. But slowly, she chips away at his seemingly impenetrable exterior, his defenses drop, and he opens up to her. Creasy's new-found purpose in life is shattered when Pita is kidnapped. Despite being seriously wounded during the kidnapping, he vows to kill anyone involved in or profiting from the kidnapping. And no one can stop him.

In Detroit, Clarence Worley goes to the movie theater alone on the day of his birthday to watch some movies. The gorgeous Alabama Whitman accidentally drops her popcorn on Clarence and they watch the movie together. Later they go to a diner for pie, and end up having a one night stand. In the morning, Alabama confesses that she is a call-girl hired to spend the night with him, but she has fallen in love with him. In the morning they get married and Clarence goes to the club where she worked to bring her some clothes. However, her pimp Drexl Spivey and his partner beat up Clarence and he reacts by killing them both. Clarence asks for Alabama's suitcase with her clothes and the other girls mistakenly give another one with cocaine. When Clarence discovers the mistake, he decides to travel with Alabama to the house of his friend, the aspiring actor Dick Ritchie, to sell the drug and travel to Mexico. He visits his father Clifford Worley and gives his address to him. But the Sicilian Mafia is the owner of the drug and a group of killers are sent to hunt down Clarence and Alabama.