Underworld: Evolution continues the saga of war between the vampires and the Lycans. The film goes back to the beginnings of the ancient feud between the two tribes as Selene, the beautiful vampire heroine, and Michael, the lycan hybrid, try to unlock the secrets of their bloodlines. This will be a modern tale of action, intrigue and forbidden love, which takes them into the battle to end all wars as the immortals must finally face their retribution.

Max Renn runs a TV channel, and when looking for new material to show--he discovers "Videodrome." His girlfriend, Nicki Brand, goes to audition for the show, and Max gets drawn into the underlying plot that uses the show as its front for a global conspiracy.

In a gritty and alternate 1985 the glory days of costumed vigilantes have been brought to a close by a government crackdown, but after one of the masked veterans is brutally murdered an investigation into the killer is initiated. The reunited heroes set out to prevent their own destruction, but in doing so discover a deeper and far more diabolical plot.